The International Transport Forum (ITF) has recently released a Research Report on Improving Safety for Motorcycle, Scooter and Moped Riders. This Report summarises the findings of the work of the Working Group on the Safety of Powered Two Wheelers set up by ITF in 2010 aiming to review trends in powered two-wheeler crashes and examine the factors contributing to these crashes and their severity. In this Report are presented in a consolidated way, a set of countermeasures targeting user behaviour, the use of protective equipment, the vehicles and the infrastructure and discussion on motorcycle safety strategies in the context of a Safe System approach.  NTUA has contributed actively to the preparation of this Report.