While vehicle safety is a key strategy to address ambitious long-term and interim goals and targets as part of an integrated safe system approach, advanced driver assistance systems (ADAS) are defined as vehicle-based intelligent safety systems which could improve road safety in terms of crash avoidance, crash severity mitigation and protection and post-crash phases. As the evaluation of ADAS is a young science and their road safety performance is of principal concern to road safety managers, the objective of the present research is to record and categorize advanced driver assistance systems as well as to discuss a variety of measures that are being promoted widely as ADAS, e-Safety or active safety measures, the knowledge about which is gradually evolving, including information on the costs and benefits of such measures. Results indicate a major categorization of ADAS regarding vehicle technologies and road casualty reduction. Furthermore, the known and unknown safety effect of specific systems is discussed including information such as the road safety problem they address, their effectiveness and benefit to cost.