Road accidents constitute a major social problem in modern societies, with very high discrepancies between the different regions and countries of the world. Within the Greek-China cooperation project i-safemodels, the objective of this research is the development of a platform for global road safety data to support macroscopic analyses. A methodological framework was designed for the development of the global data platform, combining the five road safety pillars of WHO Global Plan of Action with the concept of the SUNflower pyramid, suitably adjusted in order to serve more efficiently the needs of global road safety analysis. A set of numerous indicators and data have been selected to be included in the database from various international databases. A “big data” platform is also designed, combining transport data coming from new technologies, with the traditional road safety indicators, used for monitoring road safety performance, in order to better support decision making process.