Road safety is connected with pavement skid resistance which often triggers pavement maintenance issues. So far, many laboratory studies have been conducted trying to find a link between skid resistance and macrotexture. However, the findings cannot be extrapolated always in the field because of the multi-parametric nature of skid resistance. This triggered the present study that aims to identify key aspects of skid resistance and its main textural components, macro and microtexture. The goal is twofold: to present and assess the effect of seasonal variation on a long-term basis focusing mainly on Mediterranean climate zone and illustrate the cumulative traffic effect on skid resistance and macrotexture in the field, while paying attention to the key-role of microtexture. Study findings showed that under the effect of cumulative traffic, macrotexture and skid resistance start presenting an inverse trend. This trend seems to be related to the equilibrium phase of skid resistance performance, after which seasonal variation becomes less pronounced. In addition, the cumulative traffic in conjunction with weather variations are proved to be critical for the microtexture component. Ultimately, the study findings demonstrated the necessary awareness of constraints in using only macrotexture data to develop models for predicting field skid resistance levels.