Road crashes constitute a major social problem in modern societies, with road traffic injuries being estimated as the eighth leading cause death globally. Particularly in low and middle income countries, road traffic injuries are twice those in high income countries and still increasing. According to UN Decade of Action, there is a need to strengthen global and national efforts for casualty reduction through evidence-based approaches. The aim of this research is to develop a global road safety database that will assist governments and decision makers, both in developed and developing countries, to decide on the most appropriate road safety policies and measures in order to achieve tangible results.