The objective of this paper is the analysis of road safety management in European countries and the identification of “good practice”. A road safety management investigation model was created, based on several “good practice” criteria. Road safety management systems have been thoroughly investigated in 14 European countries on 2010, by means of interviews with both governmental representatives and independent experts, who filled in an extensive questionnaire. A reliable and accurate picture (“profile”) was created for each country, allowing country comparisons. Then, statistical methods were used to make rankings of countries, and analyse the relationship between road safety management and road safety performance. The results of the analyses suggest that it is not possible to identify one single “good practice”. Nevertheless, there were several elements that emerged as “good practice” criteria. On the basis of the results, recommendations are proposed at national and European level.