Τhis research investigates traffic and related impacts linked to the adoption of restrictions in vehicle movements associated with urban delivery operations.  A wide range of data (including land use, delivery requirements per type of service, traffic mix, traffic flows and capacities) are input to suitable models for the assessment of traffic and environmental impacts in the city of Athens, Greece. The findings suggest that restricting delivery to specific types of businesses during rush hours can lead to positive traffic and environmental impacts. The effectiveness of urban delivery restriction policies depends on the careful selection of the time periods and types of businesses for which they will apply.