In Greece, as demonstrated by the organization of the National Spatial Plan, land use planning now gives great emphasis on the development of transport infrastructure and the overall success of the regional development policy, i.e. the set of sectoral policies relating to space, must be directly linked to an integrated transport infrastructure development strategy. The socio-economic analysis of the National Strategic Reference Framework 2007-2013 (NSRF) of the Ministry of Economy and Finance, showed that, although strong growth rates have been achieved in Greece in recent years, further development of transport infrastructure and services is needed. In this context, the aim of this paper is to present an integrated strategy for the development of transportation infrastructure in the country by 2020, with the aim to develop a comprehensive national transport system , as well as to ensure high quality transport services for passengers and goods to strengthen so that the socio – economic cohesion of the country, the balanced growth and the global competitiveness within Europe are strengthened, but also to complete the Trans – European Transport Networks and thereby enhance competitiveness in the European Union.