The objective of the present research was to study the feasibility of pedestrian bridge construction in urban arterials in Athens. Initially, hazardous road segments were identified for the period 2007-2011 using the quality control method, exploiting pedestrian accident and traffic volume data for eleven arterials in Athens with high pedestrian volumes. Additionally, “before and after” analyses, using large comparison groups, were conducted for existing pedestrian bridges in arterials with similar characteristics to the aforementioned, in order to assess the potential impact of pedestrian bridge constructions on road safety. Sixteen hazardous road segments for pedestrians were identified using the quality control method. A significant heterogeneity between the results of the “before and after” analyses for the existing pedestrian bridges was observed, hindering the generalization of the accident reduction effects drawn from each individual analysis. However, based on the field data gathered for the hazardous road segments, it was deemed that four showed a high potential for pedestrian bridge construction and another four could be considered as candidate, despite their potential limitations.