The Final SafetyCube Conference will be held on 22-23 March 2018, in Vienna. SafetyCube is a research project funded by the European Commission under the Horizon 2020, the EU Framework Programme for Research and Innovation, in the domain of Road Safety. The project started on May 1st, 2015 and will run for a period of three years with primary objective to develop an innovative road safety Decision Support System (DSS) that will enable policy-makers and stakeholders to select and implement the most appropriate strategies, measures and cost-effective approaches to reduce casualties of all road user types and all severities in Europe and worldwide.